Successful treatment of relapsing Pigmented Villonodular Synovitis (PVNS) of the knee with radiosynoviorthesis

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Successful treatment of relapsing Pigmented Villonodular Synovitis (PVNS) of the knee with radiosynoviorthesis

PVNS is a rare disorder characterised by benign proliferation of synovial tissue. The treatment is surgical but relapse rate is high (8% to 46%). We report a 13 years old girl with PVNS of the left knee diagnosed in February 2003. Three months after diagnosis she underwent surgical synovectomy. Two years later important swelling of left knee with pain and limitation of movement developed and MR...

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Bilateral pigmented villonodular synovitis of the knee

Pigmented villonodular synovitis is a disorder resulting in a villous, nodular, or villonodular proliferation of the synovium, with pigmentation related to the presence of hemosiderin. These lesions are almost exclusively benign with rare reports of malignancy. Pigmented villonodular synovitis can occur in a variety of joints and at any age but most often occurs within the knee in the young adu...

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Arthroscopic treatment of pigmented villonodular synovitis of the knee.

Pigmented villonodular synovitis (PVNS) is a rare disease, with multiple forms, anatomic sites, and treatment methods having been described. During a 10-year period, 14 patients, 7 male and 7 female, average age 35 years (range, 19 to 64 years) were treated for PVNS with arthroscopic partial or total synovectomy. Average follow-up was 42 months (range, 8 to 83 months). Twelve patients had diffu...

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Localized pigmented villonodular synovitis of the knee.

Pigmented villonodular synovitis (PVNS) is a well-recognized lesion that may affect any joint but is frequently found in the knee. It is a rare condition, especially in the localized form, and is still cause for discussion regarding to its pathogenesis and treatment. We report four cases of localized PVNS each one presenting with different clinical signs and symptoms. In one of our cases, a ped...

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Complete response to imatinib in relapsing pigmented villonodular synovitis/tenosynovial giant cell tumor (PVNS/TGCT).

letters to the editor Complete response to imatinib in relapsing pigmented villonodular synovitis/tenosynovial giant cell tumor (PVNS/TGCT) Pigmented villonodular synovitis (PVNS), also known as tenosynovial giant cell tumor (TGCT), is a rare pathological entity affecting the synovium in young adults [1, 2]. Initially considered as an inflammatory reactive process, recent observations have show...

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ژورنال

عنوان ژورنال: Pediatric Rheumatology

سال: 2008

ISSN: 1546-0096

DOI: 10.1186/1546-0096-6-s1-p151